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One essential step in ensuring the endoscope remains sterile during transport is ensuring that proper wrapping materials are used. Appropriate wrapping materials provide a barrier that protects the endoscope from contamination and maintains its sterility. When an endoscope is wrapped correctly with suitable materials that are validated for sterility maintenance, it minimizes the risk of exposure to environmental pathogens or contaminants during handling and transport. This is critical because improper wrapping can compromise the sterility of the device, leading to infection risks when the endoscope is eventually used on patients.

The other options suggest practices that could jeopardize the sterility of the endoscope, such as keeping it out in the open, which exposes it to potential contaminants. Using inappropriate packing methods could fail to provide adequate protection, and applying disinfectants directly on the endoscope may further damage it or leave residue that could pose risks to patient safety.